Superscan appearance. This appearance may obscure recognition of osseous metastases. The bone scan flare phenomenon appeared within a short time after radiotherapy. Superscan is often seen in metastatic setting to the bones, notably in Carcinoma Prostate. Feb 2, 2022 · The only case report of skeletal superscan appearance in the 68 Ga PSMA PET/CT was presented by Agarwal et al. . J Nucl Med Radiat Ther 8: 320. Tc-99m (V) DMSA imaging may play a role in the evaluation of patients with equivocal bone scan findings for a superscan. May 31, 2024 · Superscan appearance due to extensive skeletal metastases on bone scintigraphy. Apr 29, 2020 · The superscan appearance in the FDG PET/computerized tomography (CT) imaging might be because of benign diseases or malignant infiltrations. In the normal patient, both the osseous May 1, 1991 · It is speculated that impaired hydrogen ion secretion in this patient with distal RTA subclinically increased bone turnover, contributing to the superscan appearance on bone scintigraphy. 99m Tc MDP planar bone scan ( a ) whole-body and ( b ) spot view images show multiple areas of intense tracer uptake due to extensive skeletal metastases with relatively decreased soft tissue tracer uptake due to decreased bioavailability. Case Discussion With advanced bony metastatic disease the uptake of radio-isotope is so profound the usual appearance of the kidneys from excreted isotope is not evident. rlu. Herein, presented the final images of the patient that demonstrated a superscan appearance in the Gallium-68 PSMA positr … bone scan which demonstrates markedly increased skeletal radioisotope uptake relative to soft tissues, in association with absent or faint genito-urinary tract activity. This case also provides a clue to the cause of skeletal uptake: note that the left kidney has been displaced inferiorly by an enlarged spleen from marked Dec 28, 2023 · The description of the superscan for conventional bone scintigraphy is widely documented, but this is not the case for 68 Ga PSMA PET/CT: at the date of writing this series of cases, and according to the literature review carried out, only four cases have been published [5-,8], so our study broadens this discussion and we propose for its Mar 1, 2003 · Bone scintigraphy with technetium-99m–labeled diphosphonates is one of the most frequently performed of all radionuclide procedures. 7%) had elevated serum ALP levels. The purpose of this review article is to describe the causes and variable features of Jul 15, 2024 · with a fever of unknown origin. Although a superscan rarely occurs in nasopharyngeal carcinoma, its appearance may represent a poor prognosis in these patients. While a superscan is relatively uncommon, its recognition is important, as it is associated with a number of important underlying diseases. Metabolic bone disease involves both the axial and appendicular skeleton and is usually homogeneous. We present an example of diffuse skeletal involvement on both 18 F-FDG PET/CT and 68 Ga DOTATATE PET/CT with a pattern similar to the superscan appearance described on skeletal scintigraphy. This case repor … The <sup>18</sup>F-fluorodeoxylucose (FDG) positron emission tomography (PET) is the gold standard imaging modality in the staging of lymphoma. Eligibility criteria included the following: Peer-reviewed Superscans were also identified secondary to hyperparathyroidism, metabolic bone disease including osteomalacia and Pagets disease. To determine if assessment of bone marrow is helpful in the diagnosis of bone invasion in patients with suspected bone superscans, the authors performed antigranulocyte antibody b … This finding may be seen in extensive hepatic involvement by malignancy such as metastatic disease, lymphoma or hepatocellular carcinoma [5-7]. Total of 6027 bone scans were examined in a 5 Superscan Appearance on Radionuclide Bone Scan From Teriparatide. Bone May 15, 2012 · Bone scan revealed diffuse skeletal metastases with superscan appearance. Feb 2, 2022 · A 64-year-old male patient with metastatic prostate carcinoma diagnosis received lutetium-177 prostate-specific membrane antigen (PSMA) treatment; however, his disease progressed. A ‘Sub-superscan’ is a term used for scan findings in which the up-take is atypical of a superscan, but the patient has extensive bone metastases, as presented in our case report. Tc-99m (V) DMSA shows increased bone uptake in patients having a superscan appearance in metastatic or metabolic bone disease. In this review, we investigate the different etiologies causing superscan and the reported frequency of superscan among different disease entities. Note that activity is increased throughout the entire skeleton, including the distal appendicular skeleton, which is characteristic of a superscan due to metabolic disorders. The term “superscan” usually refers to Apr 18, 2023 · In the prospective group, all the patients who were reported to have superscan appearance over the past 2 years of prospective period were included. This case also provides a clue to the cause of skeletal uptake: note that the left kidney has been displaced inferiorly by an enlarged spleen from marked Out of all patients with superscan, 71 patients (88. Superscans on bone scintigraphy have been described mostly in metastatic and metabolic bone diseases, with different patterns and appearances of radiotracer uptake. We review reported cases of 18-F-FDG PET/CT superscans and propose criteria for differentiating pathologic superscans from physiologic causes. Jan 1, 2017 · Besides superscan appearance was also seen in cancers such as transitional cell carcinoma of the bladder, medullary thyroid cancer, minor salivary gland cancer, Ewing's sarcoma, squamous cell carcinoma of the esophagus, and nasopharyngeal cancer, which are uncommon causes. 19 Superimposed on the diffuse uptake, brown tumors show focal areas of intense Feb 2, 2022 · The only case report of skeletal superscan appearance in the 68 Ga PSMA PET/CT was presented by Agarwal et al. . There are two main differentials - diffuse skeletal metastases and hyperparathyroidism. We present an example of diffuse skeletal involvement on both F-FDG PET/CT and Ga Jan 1, 2016 · Prostate cancer (46/80) was the most common cause of superscan appearance followed by breast cancer (10/80). Out of 6027 patients referred for bone scan, 307 patients had prostate cancer on histopathological examination. For the first time to our knowledge, a case of distal RTA is reported in association with a superscan on bone scintigraphy. For the first time to our knowledge, a case of distal RTA is reported in association with a superscan on bone scintigraphy Feb 1, 2022 · The final images of the patient that demonstrated a superscan appearance in the Gallium-68 PSMA positron emission tomography/computed tomography, which is a rare phenomenon, are presented. 1097/01. In one study, Graves' disease was associated with the highest frequency of a superscan appearance among hyperthyroid patients (Kotb et al. Neck surgery verified the presence of a parathyroid adenoma. 98%. Superscans and superscan-like appearances have also been described on fluorine-18-fludeoxyglucose positron emission tomography-computed tomography (18-F-FDG PET/CT). This case report presents lymphomatous blastic infiltration as a cause of superscan appearance in 18 F-FDG PET/CT. In contrast, a metabolic superscan tends to be more uniform and involve both the axial and more peripheral skeleton, including the distal extremities, calvarium, and mandible. The multiple lytic lesions that were seen are brown tumors (osteoclastomas) without focal Tc-99m MDP or Tc-99m MIBI uptake. The skeletal superscan-like appearance of 18 F-FDG PET/CT is a rare phenomenon in clinical practice. Total of 6027 bone scans were examined in a 5 Apr 1, 2004 · Overall incidence of superscan in this study was 1. org/10. Superscan Appearance of 68 Ga PSMA PET/CT in a Patient with Refractory Prostate Cancer 10. 53347/rID-84471 A superscan is defined as a bone scan which demonstrates markedly increased skeletal radioisotope uptake relative to soft tissues, in association with absent or faint genito-urinary tract activity. Aug 1, 2007 · A superscan is defined as a bone scan which demonstrates markedly increased skeletal radioisotope uptake relative to soft tissues, in association with absent or faint genito-urinary tract activity. rostate cancer, who subsequently developed renal osteodystrophy. Tc-99m MDP and Tc-99m MIBI scans were performed. The SUPERSCAN PM3D is an unmatched X-Y-Z surface scanner with the most innovative solutions for the industrial needs. A superscan is a rare imaging appearance characterized by a high ratio of skeletal to soft tissue radionucleotide uptake with minimal activity in the kidneys and bladder [[4], [5], [9]]. 1 | Search strategy and eligibility criteria The PubMed database was searched for relevant articles. 3: Figure 3. There were two previously reported cases with diffuse In clinical practice, it may be difficult to distinguish a metastatic bone superscan appearance from a normal bone scan. 1 - Start scanning TCP ports and ping IP addresses with this simple-to-use utility, which can help network admins manage their hosts and domains Apr 29, 2020 · Lymphoblastic Involvement of the Bone Marrow as a Cause of Superscan Appearance in 18F-Fluorodeoxyglucose Positron Emission Tomography/ Computed Tomography April 2020 Molecular Imaging and May 1, 2004 · In the prospective group, all the patients who were reported to have superscan appearance over the past 2 years of prospective period were included. Afterward, radiotherapy for bone lesions was arranged and the effects were evaluated. The appearance of a metastatic superscan differs from that of a metabolic superscan. See also Superscan Appearance of 68 Ga PSMA PET/CT in a Patient with Refractory Prostate Cancer Mol Imaging Radionucl Ther 2022;31(1):60-62 DOI: 10. A metastatic superscan tends to have uptake throughout the axial skeleton and proximal appendicular skeleton, often somewhat heterogeneous. Caution should be exercised when interpreting a bone scintigraphy in First case was a 12-year-old male child, a known case of mediastinal NB [Figure [Figure1a, 1a, anterior and and1b, 1b, posterior] and second was a 4-year-old male child, a known case of abdominal NB [Figure [Figure1c, 1c, anterior and and1d, 1d, posterior] sent to our department to rule out cortical bone involvement. Subsequently, faint or absent renal images are present due to less tracer being available for excretion. Radionuclide bone imaging is not specific, but its excellent sensitivity makes it useful in screening for many pathologic conditions. Metastatic neureoendocrine tumor to bone is well recognized. Overall incidence of superscan in our study was 1. Note the lack of uptake in the kidneys and soft tissues, indicating a “superscan appearance ” (Courtesy of JS Wu, MD, Boston) (JPG 249 kb) Multiple brown tumors with Tc-99m MDP superscan appearance and negative Tc-99m MIBI uptake Clin Nucl Med . 78800 Zehra Pınar Koç Out of all patients with superscan, 71 patients (88. (A) “Pepper-pot” or “salt and pepper” skull in HPT on a skull radiograph and (B) on computed tomography. Herein, presented the final This work reviews reported cases of 18-F-FDG PET/CT superscans and proposes criteria for differentiating pathologic superscan from physiologic causes and knowledge of the 18- F- FDG PET-CT superscan is important to the nuclear medicine physician or radiologist specializing in the interpretation of nuclear studies to avoid several diagnostic pitfalls. org (Accessed on 13 Nov 2023) https://doi. To the best of our knowledge, this is the only report of a case with lymph nodes and skeletal superscan appearance in the 68 Ga PSMA imaging. Hand radiograph with endosteal SuperScan is a free connect-based port scanning software designed to detect open TCP and UDP ports on a target computer, determine which services are running on those ports, and run queries such as whois, ping, ICMP traceroute, and Hostname lookups. Two years after the first bone scintigraphy showing multiple metastases, the patient developed renal insufficiency, hyperphosphoremia, and hypocalcemia. The differential diagnosis pertaining to a superscan pattern on skeletal scintigraphy includes diffuse osteoblastic metastasis, renal osteodystrophy, osteomalacia, and severe primary hyperparathyroidism. Keywords: Superscan, Bone scintigraphy, Diffuse bone metastasis, 99mTc- HMDP, Marrow infiltration Corresponding Author: May 1, 2023 · A superscan is an imaging appearance on the bone scintigraphy, which occurs as a result of intense skeletal uptake of radiotracers relative to soft tissue (Fig 1). 78800 May 14, 2020 · Superscan refers to increased skeletal with decreased or absent renal and soft-tissue activity on bone scan. Incidence of superscan appearance in prostatic cancer patients was 14. It has been reported in hematological diseases, solid tumors, and metabolic diseases and the specific imaging patterns may help us to find the cause of illness. Apr 18, 2023 · BS with diffuse increased skeletal radioisotope uptake with absent or faint urinary tract and soft tissue activity is defined as a superscan. Moreover, some conditions that are not clearly depicted on anatomic images can be diagnosed with bone scintigraphy. Expand 15 Mar 5, 2020 · Superscan appearance in the liver in 18 F-FDG PET/CT is usually associated with malignancy, like massive liver metastases (breast primary), primary hepatic lymphoma, diffuse angiosarcoma of the liver, secondary lymphomatous or leukemic involvement of liver etc. 2011 Mar;36(3):227-8. PCa is the most common cause of Reported cases of metabolic bone diseases producing a superscan appearance were reviewed, an … Distal renal tubular acidosis (RTA) is known to cause metabolic bone abnormalities. The present study was conducted to analyze the superscan appearance in skeletal metastatic disease and to find out its relationship with parameters such as cause, age, sex, duration of disease, serum ALP, and serum PSA. MetastasisThe superscan appearance in patients with metastatic disease occurs most frequently in those patients with prostatic, breast or gastric cancers. as a superscan appearance can be seen in diffuse metastatic bone disease. Sager S, Akgün E, Sahin OE, Akgün B, Sönmezoglu K (2017) Superscan Imaging on Ga-68 PSMA PET/CT in Prostate Cancer Patient. A superscan appearance may be caused by a prolonged delay before imaging. However, it may also occur in metabolic bone diseases such as Hyperparathyroidism, Paget disease, Osteomalacia, and myelofibrosis In metabolic bone disease, the superscan appearance tends to show homogenous involvement of the axial and the distal appendicular skeleton whereas in metastatic disease activity tends to be heterogenous and involves the axial and proximal appendicular skeletons. doi: 10. 7. Usually infective etiologies like hepatic tuberculosis, 3 Q fever hepatitis will Aug 7, 2019 · 99m Tc Tc-99 m isotope HDP nuclear bone scan in a different patient demonstrates an appearance approaching a ‘superscan’ appearance due to intense skeletal tracer distribution. Nov 1, 2006 · Request PDF | Multiple brown tumors with Tc-99m MDP superscan appearance and negative Tc-99m MIBI uptake | A 20-year-old man presented with a spontaneous left humerus fracture after minimal loading. While the typical heterogeneous appearance of metastases normally is distinct from homogeneous uptake in metabolic bone disease, the appearance of confluent disease (a superscan) can be quite similar as seen in the present patient [4-7]. Clin Nucl Med 40: 755-756. Jan 3, 2022 · Osteoblastic metastases. May 28, 2020 · Prostate cancer (46/80) was the most common cause of superscan appearance followed by breast cancer (10/80). 2 | METHODS 2. These malignancies have a predominance of spread to bone. 3% in different type of cancer patients, and the most common cause of superscan appearance was prostate cancer. Hepatic superscan appearance has also rarely been reported in non-malignant conditions including tuberculosis [8]. Radionuclide bone scan shows multiple areas of increased activity in these regions as well as the ribs and scapula. Superscans and superscan-like appearances have also been described on fluorine-18-fludeoxyglucose positron emission tomography-computed diseases causing superscan on BS and explore the reported frequency of superscan within different disease entities. , 2007). Jan 19, 2022 · A superscan is an imaging appearance on a Tc-99m diphosphonate bone scan which occurs as a result of a high ratio of bone to soft tissue tracer accumulation. Aug 7, 2019 · 99m Tc Tc-99 m isotope HDP nuclear bone scan in a different patient demonstrates an appearance approaching a ‘superscan’ appearance due to intense skeletal tracer distribution. MetastasisThe superscan appearance in patients with metastatic disease occurs most frequently in those patients with prostatic, breast or gastric cancers. Feb 1, 2017 · This work presents an example of diffuse skeletal involvement on both F-FDG PET/CT and Ga DOTATATEPET/CT with a pattern similar to the superscan appearance described on skeletal scintigraphy. diseases causing superscan on BS and explore the reported frequency of superscan within different disease entities. The term "superscan" usually refers to a characteristic pattern on skeletal scintigraphy consisting of symmetrically intense and diffuse radiotracer uptake in the skeleton with absent or diminished visualization of the genitourinary system and soft tissues. It has been reported in hematological diseases, solid tumors, and metabolic diseases and the specific imaging patterns may help us to find the cause of illness. Dec 1, 2023 · In patients presenting with a markedly elevated PSA level and extensive bone metastases, a superscan pattern can be seen on BS. The PM3D integrates patented METIS technologies for the capture of color and appearance, the calculation of 3D data, glossiness, and more into a unique solution for a highly automated and productive workflow. The search terms were ‘bone’ AND ‘superscan’ OR ‘superscan’, and the search Apart from prostate cancer, which is the most common condition associated with a superscan, other malignancies like breast cancer, lung cancer[1,2,3,4] can cause superscan appearance on bone scintigraphy. Materials and methods: The search terms were 'bone' AND 'superscan' OR 'superscan' in the PubMed database from 1980 to November 2020. Out of 307 patients with prostate cancer, 46 had superscan appearance. Liu Y. Nov 25, 2009 · More recently a super-superscan has been described, representing superimposed metastatic and metabolic superscan. Out of 6027 patients referred for bone scan, 307 patients had prostate cancer on Apr 1, 2004 · Skeletal metastases arising from a wide variety of malignancies including a few cases with superscan appearance were evaluated using 99 Tc m MDP bone scanning and 99 Tc m (V)DMSA scintigraphy. could be misinterpreted as a normal bone scan. The superscan appearance obscures some findings and this causes false negative misinterpretation of some of the malignant lesions as well. This is a report of bone scintigraphy demonstrating superimposed metastatic and metabolic superscan in a patient with prostate cancer, … In this review, we investigate the different etiologies causing superscan and the reported frequency of superscan among different disease entities. Aug 7, 2024 · A superscan is an imaging appearance on a Tc-99m diphosphonate bone scan which occurs as a result of a high ratio of bone to soft tissue tracer accumulation. 3% in different type of cancer patients, and the most common cause of Superscan appearance was prostate cancer. Case study, Radiopaedia. 4274/mirt. Oct 1, 2017 · The term 'superscan' usually refers to a characteristic pattern on skeletal scintigraphy consisting of symmetrically intense and diffuse radiotracer uptake in the skeleton with absent or Aug 7, 2024 · Radiographic appearance. Data availability statement The appearance of a superscan is frequently accompanied by an abnormal titer of serological markers IgG-VCA and IgA-VCA, liver metastases, and poor survival. Metastatic disease is the most common cause of a superscan and typically involves the axial skeleton. 99m Tc-MDP BS showed Feb 1, 2022 · The only case report of skeletal superscan appearance in the 68 Ga PSMA PET/CT was presented by Agarwal et al. Distal renal tubular acidosis (RTA) is known to cause metabolic bone abnormalities. The skeletal superscan-like appearance of 18F-FDG PET/CT is a rare phenomenon in clinical practice. Typically, this has an appearance of multiple focal lesions. 6. Fig. Jan 28, 2014 · In bone imaging the term “superscan” has been used to describe the appearance of high skeletal uptake of radionuclide combined with low background activity (Osmond etal, 1975). It is usually accompanied by absent or faint renal activity (Sy et al, 1975). Prostate cancer (46/80) was the most common cause of superscan appearance followed by breast cancer (10/80). These malignancies have a predominance of spread Classical superscan appearance. Incidence of superscan in prostate cancer Superscan appearance can sometimes be difficult to spot but is easy to make when the absent renal uptake is noticed. Data availability statement Feb 2, 2022 · Herein, presented the final images of the patient that demonstrated a superscan appearance in the Gallium-68 PSMA positron emission tomography/computed tomography, which is a rare phenomenon. “Superscan” appearance is an interesting terminology that has long been in use in nuclear medicine. Super-superscan on a bone scintigraphy. Apr 1, 1996 · The appearance of a superscan is frequently accompanied by an abnormal titer of serological markers IgG-VCA and IgA-VCA, liver metastases, and poor survival. The examination is most commonly performed using the radiotracer Technetium-99m (Tc99m) complexed to a diphosphonate, either methylene diphosphonate (MDP) forming Tc99m-MDP or hydroxydiphosphonate (HDP) forming Tc99m-HDP. (2015) Metastatic Prostate Carcinoma Presenting as a Superscan on 68 Ga-PSMA PET/CT. Repeat bone scintigraphy demonstrates significantly different appearance from that of the first study. Aug 14, 2023 · Skeletal scintigraphy, commonly referred to as a bone scan (BS), is a valuable and versatile nuclear medicine tool. Keywords: PSMA, 68Ga, Lu-177, prostate cancer May 7, 2014 · Download SuperScan 4. Intense osteoblastic activity in the bones causes diminished renal and background soft tissue uptake. Diffuse bone metastasis, which is common in NPC, were indeterminate on images showing superscan pattern or Jul 1, 2007 · The causes and variable features of a superscan are described and patterns which may aid in defining the underlying cause for the scan are depicted to help identify the underlying disease in such cases. Usually infective etiologies like hepatic tuberculosis, 3 Q fever hepatitis will Mar 5, 2020 · Superscan appearance in the liver in 18 F-FDG PET/CT is usually associated with malignancy, like massive liver metastases (breast primary), primary hepatic lymphoma, diffuse angiosarcoma of the liver, secondary lymphomatous or leukemic involvement of liver etc. However, the extremities typically have a greater level of increased uptake with secondary hyperparathyroidism than is expected with metastatic disease. Out of 6027 patients referred for bone scan, 307 patients had prostate cancer on Jun 19, 2018 · Lawal I, Vorster M, Boshomane T, Ololade K, Ebenhan T, et al. For the first ti Metastatic neureoendocrine tumor to bone is well recognized. The incidence of superscan appearance in prostatic cancer patients was Feb 21, 2023 · Bone scans may reveal diffuse skeletal uptake of radiopharmaceutical with a superscan appearance that can be confused with metastatic disease. This appearance has been associated with two main pathological groups. Here we present a case of colon carcinoma with metastatic superscan on 99m Tc-MDP bone scintigraphy, a very rare cause for metastatic superscan. Vargo-Gogola T, Rosen JM (2007) Modelling breast cancer: one size does not a superscan, especially because of the fact that the kidneys were not shown. Mettler FA and Guiberteau MJ. No evidence of radio-isotope excretion in the kidneys - a superscan. That appearance has been described as “too good” or beautiful scan and it include some Jul 14, 2024 · The skeletal superscan-like appearance of 18 F-FDG PET/CT is a rare phenomenon in clinical practice. 2006 Oct;31(10):640-3. Cathy Lee Ching, MD, and Suresh Kumar, MD University of Miami Miller School of Medicine/JFK Medical Center Palm Beach Regional Campus, Atlantis, Florida Jan 1, 2015 · The appearance of a metastatic superscan is characterized by abnormally increased skeletal uptake in a distribution similar to that of the bone marrow, that is, the axial and proximal appendicular skeleton to a greater degree than the appendicular skeleton. galenos. It is well known that superscans are associated with a poor prognosis among cancer patients, but there is a lack of information on whether superscans are associated with the prognosis among patients Apart from prostate cancer, which is the most common condition associated with a superscan, other malignancies like breast cancer, lung cancer [1] [2] [3][4] can cause superscan appearance on bone Primary: over secretion of PTH from parathyroid adenoma or hyperplasia, bone scan unremarkable Secondary: low blood Ca++ due to renal failure or osteomalacia, therefore secretion of PTH shows most extreme bone scan appearance Tertiary: autonomous parathyroid gland following prolonged hypocalcaemia, may start as secondary but even after calcium corrected, gland continues to secrete PTH Distal renal tubular acidosis (RTA) is known to cause metabolic bone abnormalities. Absence of renal uptake. fb. Superscans were also identified secondary to hyperparathyroidism, metabolic bone disease including osteomalacia and Pagets disease. With metastatic disease (most commonly prostate or breast cancer), the uptake is heterogeneous or patchy and favours the axial skeleton. 0000237968. Whole body planar scans were obtained at 3 h and 24 h after injection of 740 MBq 99 Tc m MDP and 5 days later at similar times after injection of 555 MBq Apr 29, 2020 · The superscan appearance in the FDG PET/computerized tomography (CT) imaging might be because of benign diseases or malignant infiltrations. A 64-year-old male patient with metastatic prostate carcinoma diagnosis received lutetium-177 prostate-specific membrane antigen (PSMA) treatment; however, his disease progressed. The search terms were ‘bone’ AND ‘superscan’ OR ‘superscan’, and the search Sep 29, 2020 · Superscan appearance in the liver in 18 F-FDG PET/CT is usually associated with malignancy, like massive liver metastases (breast primary), primary hepatic lymphoma, diffuse angiosarcoma of the liver, secondary lymphomatous or leukemic involvement of liver etc. Clin Nucl Med. Intense osteoblastic activity in the bones causes diminished renal and background soft t Superscan is defined as a special appearance of bone scan, characterized by homogeneous and symmetrical increased uptake of bone radiopharmaceuticals in the skeleton. Background. 2020. We present an example of diffuse skeletal involvement on both F-FDG PET/CT and Ga DOTATATE PET/CT with a pattern similar to the superscan appearance described on skeletal scintig … The appearance of the bone scan is consistent with a "metabolic superscan," in this case due to secondary hyperparathyroidism (renal osteodystrophy). Aug 1, 2022 · 2686 Introduction: Superscan on Bone scintigraphy is characterized by diffusely increased tracer uptake throughout the skeleton accompanied by decreased renal visualization. Tc99m is the most common radionuclide used in nuclear Jan 19, 2022 · A superscan is an imaging appearance on a Tc-99m diphosphonate bone scan which occurs as a result of a high ratio of bone to soft tissue tracer accumulation. Whole-body bone scintigraphy (bone scan) using a 99mTc-labelled pharmaceutical is one of the most commonly performed radionuclide examinations. hosphatemia, whereas the biopsy of a lytic lesion (right humerus) showed only a few macrophages and multinuclear giant cells. (8). Chapter 9: Skeletal System. [1,2] Initially, by definition, this terminology applied to a pattern on bone scintigraphy that assumes a condition in which the 99 mTc-mthylene-diphosphonate is perfectly taken up in the skeletal system, and no background activity is noticed. References. Introduction A superscan is defined as a bone scan which demonstrates markedly Radiographic appearance. To the best of our knowledge, this is the only report of a case with lymph nodes Sep 26, 2023 · A superscan is a rare imaging appearance char-acterized by a high ratio of skeletal to soft tissue radionu-cleotide uptake with minimal activity in the kidneys and blad-der [4,5,9]. In metabolic bone dis-ease, the superscan appearance tends to show homogenous involvement of the axial and the Fig. With metabolic bone disease, the increased uptake is often more homogeneous and may extend to the distal appendicular skeleton. 88074. Usually infective etiologies like hepatic tuberculosis, 3 Q fever hepatitis will Bickle I, Superscan: prostate cancer. breixeannjwqheiqftidjzvtqrezpkodbtztobmhqemptzes